Search on: ANTIGEN, PROLIFERATING CELL NUCLEAR 
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Descriptor English:   Proliferating Cell Nuclear Antigen 
Descriptor Spanish:   Antígeno Nuclear de Célula en Proliferación 
Descriptor Portuguese:   Antígeno Nuclear de Célula em Proliferação 
Synonyms English:   Antigen, Proliferating Cell Nuclear
PCNA  
Tree Number:   D12.776.660.740
D23.050.290.750
D23.101.140.600
Definition English:   Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types. 
History Note English:   95; was PROLIFERATING CELL NUCLEAR ANTIGEN (NM) 1983-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   32064 
Unique Identifier:   D018809 

Occurrence in VHL:
 

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